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Active Surveillance Patients International

A beginner’s guide to Active Surveillance

What Is Active Surveillance?

Active Surveillance is a structured way to manage certain prostate cancers with regular monitoring instead of immediate surgery, radiation, or another treatment.

You have time

If Active Surveillance is a realistic option, you have time to understand your diagnosis, ask questions, and consider your options. You should not be rushed into immediate treatment.

Created by patients, survivors, and advocates, ASPI helps men and their families understand Active Surveillance, take an informed role in their care, and connect with others who have faced similar decisions. This guide explains the basics in plain language.

Patient and partner speaking with a doctor during a calm medical consultation
A calm, step-by-step approach can make the first decisions feel more manageable.

What Active Surveillance means

The cancer is monitored carefully instead of treated immediately.

The cancer is monitored, not ignored

Planned follow-up

Active Surveillance uses planned PSA tests, appointments, and imaging to watch the cancer over time. Additional tests are added when they are needed to clarify a result. This is different from watchful waiting, which generally uses less intensive testing and focuses more on symptoms.

It can be a long-term approach

Many men remain on Active Surveillance for years, and some stay on it indefinitely without needing treatment. Surgery, radiation, or another treatment remains an option only if later findings show that a different approach is needed.

Who may be eligible

Eligibility depends on the cancer’s risk and your overall situation.

Low risk
Usually Grade Group 1, also called Gleason 3+3, with PSA, examination, and biopsy findings that show a low-risk cancer confined to the prostate.
Favorable intermediate risk
Some men with a small amount of Grade Group 2, also called Gleason 3+4, may also be considered when the other findings are favorable.

Your results are considered together

Your doctor considers your Grade Group, PSA and PSA density, biopsy, examination, and MRI together. Micro-ultrasound or biomarker tests may add useful information in some situations.

The plan also needs to work for you

Active Surveillance requires regular testing and appointments. Your overall health, priorities, comfort with monitoring, and ability to keep up with the schedule are part of the decision.

How monitoring works

Your care team sets a schedule based on your results and adjusts it when needed.

What follow-up may include

  • PSA blood tests
  • Appointments to review results and concerns
  • MRI, with micro-ultrasound in some settings
  • A repeat biopsy only when needed to clarify or reassess the cancer
  • Biomarker tests when they may add useful information

Results are looked at together

PSA can change for reasons other than cancer growth. Decisions are based on patterns over time and the combined results of imaging, biopsy, examination, and other tests.

What happens if a result changes

One changed result is reviewed in context before the plan changes.

A new result is confirmed and reviewed

A PSA rise, imaging change, or other new result does not decide the next step by itself. Your care team may repeat a blood test, review imaging, seek another opinion, or consider a biopsy if an important question remains.

After review, the plan may stay the same, monitoring may become closer, or other options—including treatment—may be discussed. Many men continue on Active Surveillance. A change in the plan is not inevitable and is not a failure.

What to do next

Take these three questions to your next appointment.

Helpful resources

When you are ready to learn more, these ASPI resources can help you understand terms, prepare questions, and learn from patients and experts.

Active Surveillance glossary resource preview

Learn the language

Use the glossary to understand common terms in appointments, reports, and test results.

Open the Glossary
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